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KMID : 0613319960020010054
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Journal of the Korean Bone and Joint Tumor Soceity
1996 Volume.2 No. 1 p.54 ~ p.59
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Survival Rate and Prognostic Factors of Liposarcoma
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Kim Jae-Do
Son Jeong-Hwan
Park Jeong-Ho
Park Keon
Hong Young-Gi
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Abstract
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Liposarcoma is second in frequency only to malignant fibous histocytoma among the soft tissue sarcoma.Many different factors which might affect the survival rate of liposarcoma have been report-ed by many authors. The purpose of this study was to evaluate survival rate of liposarcoma and define the prognostic factors that affected survival rate. The authors analysed retrospectively 17 patients of liposarcoma in extremities from May 1984 to Dec. 1995 who had been treated in department of orthopaedic surgery of Kosin University Medical Center. All cases were resected with marginal or wide margin. There were 9 men and 8 women. The mean age was 48 years. The follow-up period ranged from 15 to 96 months. We compared the pro-nosis of the patients with several factors; age ,sex,surgical staging,size,site,histologic type and treatment modality. At last follow-up,the presence of local recurrence was in 3 cases and the presence of lung metasta-sis was in 8 cases. The survival rates by Kaplan-Meier product limit method at 2 years and 5 years were 87% and 57% respectively. The statististically significant difference was estimated in histologic type,but was not estimated in age,sex surgical staging,size,site and treatment modality.In conclusion,the histologic type is con-sidered as the most important factor of the prognosis in liposarcoma. Although it was too tew patients for the differences to be statistically significant,we consider that surgical staging,site,size,the radio-therapy and chemothrapy in liposarcoma will affect the prognosis.
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KEYWORD
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Liposarcoma, Survival rate, Prognositc factors
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